- Title
- Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait
- Creator
- Roeder, Luisa; Breakspear, Michael; Kerr, Graham K.; Boonstra, Tjeerd W.
- Relation
- iScience Vol. 27, Issue 3, no. 109162
- Publisher Link
- http://dx.doi.org/10.1016/j.isci.2024.109162
- Publisher
- Cell Press
- Resource Type
- journal article
- Date
- 2024
- Description
- Walking is a complex motor activity that requires coordinated interactions between the sensory and motor systems. We used mobile EEG and EMG to investigate the brain-muscle networks involved in gait control during overground walking in young people, older people, and individuals with Parkinson's disease. Dynamic interactions between the sensorimotor cortices and eight leg muscles within a gait cycle were assessed using multivariate analysis. We identified three distinct brain-muscle networks during a gait cycle. These networks include a bilateral network, a left-lateralized network activated during the left swing phase, and a right-lateralized network active during the right swing. The trajectories of these networks are contracted in older adults, indicating a reduction in neuromuscular connectivity with age. Individuals with the impaired tactile sensitivity of the foot showed a selective enhancement of the bilateral network, possibly reflecting a compensation strategy to maintain gait stability. These findings provide a parsimonious description of interindividual differences in neuromuscular connectivity during gait.
- Subject
- age; neuroscience; techniques in neuroscience; walking
- Identifier
- http://hdl.handle.net/1959.13/1500223
- Identifier
- uon:54882
- Identifier
- ISSN:2589-0042
- Rights
- x
- Language
- eng
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